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11 articles

The Control Group Knew. It Worked Anyway. Now What?

The Control Group Knew. It Worked Anyway. Now What?

Open-label placebo trials keep producing a result that shouldn't exist: patients get better from pills they know are empty. Here's why that finding is messier than the headlines suggest — and what it exposes about the sacred architecture of the randomized controlled trial.

The Toughest Opponent in Medicine Is a Pill Made of Nothing

The Toughest Opponent in Medicine Is a Pill Made of Nothing

Sugar pills keep winning, and it's not because they're magical. It's because the bar they're measured against — the humble placebo response — has been quietly climbing for decades. Here's what that means for every 'breakthrough drug' headline you'll read this year.

Your Heatwave Is Not a Trend: The Enormous Math Behind One Global Thermometer

Your Heatwave Is Not a Trend: The Enormous Math Behind One Global Thermometer

Every summer, a record-breaking heatwave or a freak blizzard gets trotted out as proof of whatever someone already believed about climate. Here's why one storm settles nothing — and how scientists stack thousands of weather stations and a century of data to find a signal that refuses to hide.